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USP25 and 28 inhibitor AZ-2
CAS No. 2165322-95-0
USP25 and 28 inhibitor AZ-2 ( USP25/28 inhibitor AZ2 )
产品货号. M13456 CAS No. 2165322-95-0
USP25 and 28 inhibitor AZ-2 is apotent, selective, dual USP25/28 inhibitor with IC50 of 0.9/0.9 uM, respectively.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥7857 | 有现货 |
|
| 50MG | ￥16038 | 有现货 |
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| 100MG | ￥20250 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称USP25 and 28 inhibitor AZ-2
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述USP25 and 28 inhibitor AZ-2 is apotent, selective, dual USP25/28 inhibitor with IC50 of 0.9/0.9 uM, respectively.
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产品描述USP25 and 28 inhibitor AZ-2 is apotent, selective, dual USP25/28 inhibitor with IC50 of 0.9/0.9 uM, respectively; shows a high degree of selectivity over other deubiquitinases (USP4,7 etc.); demonstrates target engagement against both USP25 and USP28 in cells, elicits modulation of both the total levels and the half-life of the c-Myc oncoprotein in cells, and also induces apoptosis and inhibits cell viability in a range of cancer cell lines.
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同义词USP25/28 inhibitor AZ2
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通路Proteasome/Ubiquitin
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靶点DUB
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受体DUB
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研究领域——
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适应症——
化学信息
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CAS Number2165322-95-0
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分子量420.23
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分子式C17H17BrF3NO3
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纯度>98% (HPLC)
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溶解度10 mM in DMSO
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SMILESC1=CC(=CC(=C1)OC(F)(F)F)COC2=C(C=C(C=C2)Br)CNCCO
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化学全称2-((5-bromo-2-((3-(trifluoromethoxy)benzyl)oxy)benzyl)amino)ethan-1-ol
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Wrigley JD, et al. ACS Chem Biol. 2017 Nov 28. doi: 10.1021/acschembio.7b00334.
产品手册
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